NGN Quiz: Serious Side Effects of Magnesium Sulfate Spotting the Most Serious Side Effect of Magnesium Sulfate in Preeclampsia: Test Your Knowledge with this Next Generation NCLEX (NGN) Practice Question! A 25-year-old pregnant woman is admitted to the hospital with preeclampsia. She is started on magnesium sulfate. Which of the following side effects of magnesium sulfate is the most serious? A. Hypotension B. Nausea and vomiting C. Drowsiness D. Respiratory depression Δ