Toxidromes Cheat Sheet: What Every Nurse Should Know

Toxidrome What Every Nurse Should Know

A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5 big ones to know:

Anticholinergic: low potency antipsychotics, oxybutynin, ACh receptor antagonists (ipratropium, atropine, scopolamine)
Cholinergic: ACh recptor agonists (pilocarpine), AChEIs (organophosphates, phyostigmine)
Opioid: Morphine, heroin, hydromorphone, etc
Sympathomimetic: epinephrine, cocaine, amphetamine (Aderol), methylphenidate (Ritalin)
Sedative-Hypnotic: Benzodiazepines, barbituates, “Z-drugs” (zopiclone, zolpidem), antihistamines

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