Factors Affecting Prognosis for Clients with Malignant Melanoma: An NCLEX Practice Quiz Factors Affecting Prognosis for Clients with Malignant Melanoma: An NCLEX Practice Quiz What factors influence the prognosis for a client with malignant melanoma?* 1. The amount of ulceration of the lesion. 2. The age of the client. 3. The location of the lesion on the body. 4. The thickness of the lesion. Δ